Molecular origin of the extreme mechanical strength of an ester bond containing pathogen surface protein

Speaker : Prof. Yi Cao Affiliation : Nanjic University China, Institute of Biomedical Medicine Region : LatAm Year : 2021 Language : English Explore the mechanical properties of cell surface proteins in gram-positive bacteria using single molecule AFM. Investigate the role of intramolecular covalent bonds, such as isopeptide and ester bonds, in stabilizing protein structures and implications for bacterial adhesion and infection mechanisms.